Health knowledge about inner ear2-2


Ototoxic drugs refer to the toxic and side effects of these drugs that mainly damage the eighth pair of cranial nerves (the auditory nerve). There are nearly one hundred kinds of ototoxic drugs known, commonly used aminoglycoside antibiotics (streptomycin, kanamycin, neomycin, gentamicin, etc.), macrolide antibiotics (erythromycin, etc.) ), tetracyclines (tetracycline, etc.), amido alcohols (chloramphenicol, etc.), anticancer drugs (vincristine, 2-nitroimidazole, cisplatin), salicylate antipyretic analgesics (aspirin) Etc.), antimalarial drugs (quinine, chloroquine, etc.), loop diuretics (furosemide, plume uric acid), antihepatic cholinergic agents (Paulan Bolin), thallium compound agents (reaction stop), etc. Among them, the ototoxicity of aminoglycoside antibiotics is the most common clinically. These drugs, whether systemic or local, can enter the fetus through the blood circulation and damage the hearing system.

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